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Epitome has filed a patent application for a (counter-intuitive) dose-response algorithm for the appropriate prescription of warfarin and other coumarins. Controlling the effects of prophylactic anti-coagulation is a serious medical issue with approximately 3 million patients in the US on trial and error dose adjustment regimes. Managing anticoagulation consumes vast amounts of clinic time, and hospital time when overdoses result in bleeding. The algorithm, as well as an innovative medication to reduce anticoagulant fluctuation, are scheduled for investigational trials.
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